Betamethasone It is a medicine that belongs to the group of corticosteroids or corticosteroids. These are synthetic glucocorticoids that have immunosuppressive and anti-inflammatory effects. Topical derivatives of betamethasone are used as anti-inflammatories in the treatment of dermatoses that respond to corticosteroids.
What indications does betamethasone have?
Because of its immunosuppressive effects, betamethasone is used to treat symptoms caused by a sharp decrease in corticosteroid levels in the body. It works by decreasing the release of substances that cause inflammation. Therefore, it is useful in diseases that occur with excessive inflammation.
Between the indications of betamethasone, are included:
- Insufficiency of corticosteroids in the body primary or secondary, such as Addison's disease.
- Shock situations caused by hemorrhage, trauma or serious infection.
- Rheumatic diseases.
- Ulcerative Colitis
- Skin disease that respond to corticosteroids, such as exfoliative dermatitis, urticaria, erythema multiforme or severe psoriasis.
- Ophthalmic diseases: severe acute and chronic allergic and inflammatory processes such as allergic conjunctivitis, keratitis, allergic corneal marginal ulcers or ophthalmic shingles.
How is it used?
Betamethasone It is marketed in different forms of oral, parenteral and topical administration. The appropriate dose of this corticosteroid is different for each patient and will be adjusted according to the disease to be treated.
Topical preparations are administered by placing a thin layer of product in the area to be treated.. However, intralesional administration is indicated for the treatment of keloids, chronic lichen simplex, lupus erythematosus or alopecia areata.
Remember that you should avoid abrupt suspension of treatment. Especially when they are prolonged, as the corticosteroid withdrawal syndrome may appear. The symptoms that may appear are:
- General discomfort.
- Weakness and muscle pain.
- Nausea and vomiting.
- Respiratory distress.
- Decrease in blood pressure and blood glucose.
Discover: What is Addison's disease?
Contraindications and precautions for use
Between the contraindications regarding the use of betamethasone, are included:
On the other hand, you have to have special Caution when using betamethasone in case of illness how:
- Bone diseases
- Ulcer of stomach or intestine.
- Mellitus diabetes.
- Heart, liver or kidney diseases.
- Thyroid conditions.
Regarding the use of betamethasone during breastfeeding, there are data that indicate that the amount that passes into milk can be significant. For this reason, in prolonged treatments it is advisable to use corticosteroids known for their lack of milk.
However, It is compatible with breastfeeding provided it is used in a timely manner and in short treatments. However, in these cases, milk production must also be monitored.
When betamethasone is used in the delivery, it can delay the rise of milk and decrease the amount during the first week
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Adverse reactions of betamethasone
Short-term treatments usually do not cause adverse reactions.. However, long treatments can cause atrophy of the adrenal glands.
Betamethasone, when administered topically, it can cause adverse reactions which, if they are intense or do not disappear, make it necessary to go to the specialist.
How adverse reactions, may appear:
- Unwanted hair growth.
- Changes in skin color.
However, there are other symptoms that may appear, such as severe hives, redness, swelling or signs of skin infection at the site of application.
When topical betamethasone is applied in children, there is an increased risk of side effects, including stunted growth and weight gain.
On a systemic level, in prolonged treatment, the intensity of the associated adverse effects increases with the dose, as well as their duration.
Some of the side effects that may appear after oral or parenteral administration Betamethasone are:
- Swollen eyes.
- Respiratory problems.
- Urinate more frequently.
- Increased thirst.
- Dark stool
- Vision changes.
Betamethasone is a corticosteroid that is used primarily topically. It is used to treat discomfort caused by different skin problems. It should always be used following the instructions of the specialist.